Volatile Organic Compounds (VOCs) (D) are chemicals often found in building materials, such as paints, adhesives, and finishes, and are associated with health risks, including asthma, chronic obstructive pulmonary disease, and certain cancers. VOCs release harmful gases that contribute to indoor air pollution, and LEED encourages using low-VOC materials to protect occupant health. PVCs (B) and CFCs (C) are harmful to the environment but are not directly linked to these health conditions.