Auto-Suppression lists are lists of subscribers who should not receive certain types of emails, such as promotional or transactional emails. Auto-Suppression lists can be configured for different send classifications, such as Commercial or Transactional, and can be applied to specific sender profiles or the entire account. By configuring an Auto-Suppression list for the Commercial classification, the marketer can ensure that the group of subscribers will not receive any promotional emails sent with that classification.