TheU.S. Food and Drug Administration (FDA)requires aMedication Guide (MedGuide)to be provided when dispensing certain medications that have significant safety concerns.Zyprexa (Olanzapine), anatypical antipsychotic, requires aMedication Guidedue to serious risks such as:
* Increased mortality in elderly patients with dementia-related psychosis
* Metabolic side effects(e.g., weight gain, hyperglycemia, and dyslipidemia)
* Neuroleptic malignant syndrome (NMS)
* A. Zafirlukast# Incorrect; while used forasthma(leukotriene receptor antagonist), it doesnot require a Medication Guide.
* B. Zestril (Lisinopril)# Incorrect; anACE inhibitorfor hypertension, it doesnot require a Medication Guide.
* C. Zinc# Incorrect; adietary supplementthat does not require a Medication Guide.
Other Answer Choices Explained:References:
* FDA Medication Guide Requirements for Olanzapine (Zyprexa)
* PTCB PTCE Exam Content Outline (Medication Safety & Patient Counseling)