The core parameters that impact thermal comfort in a mechanically conditioned space include air temperature, humidity, air movement, mean radiant temperature of surrounding surfaces, metabolic rate, and clothing insulation. These factors collectively influence an individual's thermal perception and comfort within an indoor environment. Air temperature and humidity affect the thermal sensation directly, while air movement can enhance the feeling of coolness or warmth. The mean radiant temperature impacts how heat is exchanged between the human body and surrounding surfaces. Metabolic rate and clothing insulation are personal factors that determine how individuals generate and retain heat. Understanding and optimizing these parameters are crucial for creating indoor environments that support occupants' thermal comfort, aligning with the WELL Building Standard's Thermal Comfort concept, which aims to provide a comfortable thermal environment that supports the health and well-being of building occupants.