For backing up a 3-node Microsoft SQL Always On cluster running in a VMware environment with the specified Recovery Point Objectives (RPOs), the most suitable option is A: Veeam Backup and Replication - Create a VMware backup job, include the 3 nodes of the cluster. Use Application-Aware Processing to back up the transaction logs every 15 minutes. This approach allows for the entire SQL cluster nodes to be backed up as part of a regular VM backup job, which satisfies the 1-day RPO for the cluster nodes. The Application-Aware Processing feature of Veeam Backup & Replication ensures that the SQL databases are in a consistent state during backup. Moreover, this feature allows for the transaction logs to be backed up separately at a more frequent interval, in this case, every 15 minutes, meeting the 15-minute RPO requirement for the log files. This dual approach ensures comprehensive protection for both the SQL cluster nodes and the critical transaction logs, aligning with the specified RPOs.