Explanation
To completely block a material for procurement in a plant, you can use the following methods:
Create an entry in the source list with a blocking indicator and NO supplier, which means that you prevent the system from finding any valid source of supply for the material in the plant.
Use a relevant plant-specific material status in the material master, which means that you restrict the procurement transactions that are allowed for the material in the plant. For example, you can use material status 01 (Procurement blocked) to block all procurement transactions. References: SAP S/4HANA Sourcing and Procurement | SAP Learning, Course S4520, Unit 3, Lesson 2.