According to the web search results, one recommended configuration change to improve throughput for a custom backup application that requires a 2TB disk and runs on Windows is to span the 2TB disk across four vDisks. Spanning is a technique that allows you to create a single logical disk from multiple physical disks. Spanning can improve throughput by distributing I/O requests across multiple disks and reducing contention5. To span a disk across four vDisks, the administrator should create four vDisks of equal size (500 GB each) and attach them to the VM. Then, in Windows Disk Management, create a spanned volume from the four vDisks and format it as NTFS6.