Explanation:
Box 1: No
Need AD FS for MF
Note: Azure Active Directory (Azure AD) Pass-through Authentication allows your users to sign in to both on-premises and cloud-based applications using the same passwords. This feature is an alternative to Azure AD Password Hash Synchronization (see Box 2).
Box 2: Yes
Password hash synchronization is one of the sign-in methods used to accomplish hybrid identity. Azure AD Connect synchronizes a hash, of the hash, of a users password from an on-premises Active Directory instance to a cloud-based Azure AD instance.
Password hash synchronization is an extension to the directory synchronization feature implemented by Azure AD Connect sync. You can use this feature to sign in to Azure AD services like Office 365. You sign in to the service by using the same password you use to sign in to your on-premises Active Directory instance.
Box 3: Yes
If your organization is federated with Azure AD, you can use Azure Multi-Factor Authentication to secure AD FS resources, both on-premises and in the cloud. Azure MFA enables you to eliminate passwords and provide a more secure way to authenticate.
References:
https://docs.microsoft.com/en-us/azure/active-directory/hybrid/whatis-phs
https://docs.microsoft.com/en-us/windows-server/identity/ad-fs/operations/configure-ad-fs-and-azure-mfa