A. Storage fragmentation may occur over time.

B. Provisioning speed is slower when compared to full clones.

C. Storage and virtual machine (VM) migration may be more complex when compared to full clones.

D. Higher storage space is required when compared to full clones.
https://support.citrix.com/article/CTX224040
https://docs.citrix.com/en-us/citrix-virtual-apps-desktops/1912-ltsr/citrix-virtual-apps-and-desktops-7-1912-ltsr.pdf

E. Storage space should be closely monitored.