Enabling the EndPoint Attribute Filter will have the Cisco ISE profiler only to keep significant attributes and discard all other attributes. Significant attributes are those used by the Cisco ISE system or those used specifically in a endpoint profiling policy or rule.
https://www.cisco.com/c/en/us/td/docs/security/ise/2-
4/admin_guide/b_ISE_admin_guide_24/m_cisco_ise_endpoint_profiling_policies.html#ID481