NAPLEX Exam Dumps | Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a Sulfamethoxazole/Trimethoprim

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NABP
North American Pharmacist Licensure Examination
NABP.NAPLEX.v2022-05-25.q74
Question 22

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Question 22/74

Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a Sulfamethoxazole/Trimethoprim intravenously for PCP. You know the dose is 15mg/kg/day (based on TMP component) divided q6h.
How many milliliters of Sulfamethoxazole/Trimethoprim of 400mg/80mg/5ml would you need for single dose? Patient weighs 80kg.

A. 18.75 mL

B. 75 mL

C. 15 mL

D. 50 mL

E. 16.5 mL

Correct Answer: A

Explanation
80kg person = 15mg/kg/day = 1200mg/day 80mg /5ml = 1200mg/X X= 75mL/day / 4 doses = 18.75 mL per dose

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